You may get the below message in your browser console.
HTTP Error 401.3 - Unauthorized
You do not have permission to view this directory or page because of the access control list (ACL) configuration or encryption settings for this resource on the Web server.
You may face this issue because Authenticated users did not have read access to %windir%\Microsoft.net\Framework64\v4.030319
You will need to add authenticated users. You can also reset the default permissions for the aspnet_filter.dll 32 and 64 bit folders. It can be residing inside %windir%\Microsoft.net\Framework64\v4.030319
You can also face this issue if your .aspx files inside wwwroot don't have the required permissions.